19 of the Russian's twenty-one titles have been earned on hard surfaces
A revitalized Medvedev secured his first trophy for 882 days with victory over Corentin Moutet in the competition championship match.
The athlete, a ex- world number one, has endured a difficult year, winning just one match at the major tournaments and experiencing a meltdown at the New York tournament.
Medvedev's inconsistency on the professional circuit - and difficulties with his serve in especial - resulted in him falling of the top ten and ultimately parting ways with former trainer Gilles Cervara.
Currently working with Thomas Johansson and Rohan Goetzke, he has gradually advanced in the last few weeks - peaking in a tightly fought three-set win over Frenchman Moutet.
This represents Medvedev's initial trophy following the Rome competition and initial on a hard surface from that period of the previous year.
The win also means Medvedev has achieved twenty-one titles at twenty-one various events.
"This marks the first occasion I am participating in a tournament with my children at once, so to secure a title is particularly special," commented tennis professional the champion.
"This championship is in honour of my younger daughter my daughter, because the first title I got when my first daughter her name was born was for her."
The tennis star, the past champion, had failed in his last six championship matches, featuring in that event in the past months.
Medvedev's counter-punching play style and frequent outbursts on the playing surface had led observers to wonder if his skill to play at the elite level was concluded.
However the player has altered his approach in the past month, attempting to approach the net and compete assertively, backed up by an enhanced serving game.
Medvedev fought back from a break down in the initial set against the difficult Frenchman, winning four of the concluding five games to take the lead.
Both players swapped break points in the following set before the challenger, striving for his initial tour victory, seized the initiative to create a decider.
The opponent defended 4 early chances in a competitive third set before Medvedev broke to fifteen to secure the win.
Fittingly, Medvedev earned the title with a rally at the net area, with the Frenchman failing to control a shot after two hours and 38 minutes.